Physician's Reserve is a phrase used to describe one of our most powerful and effective anti-aging skin care products developed specifically for the eyes. Originally labeled for private clinics, The Eye Complex is the result of 2 years of research and development by Civant Pharma. The Eye Complex plays a vital role in the reduction of dark circles, fine lines, wrinkles, and puffiness around the eyes. It strengthens and repairs the skin's barrier thereby contributing to the reconstruction of the dermis. The Eye Complex contains active anti-oxidants which helps strengthen native collagen and elastin matrix, improves cell cohesion, enhancing water retention and reducing skin dryness. It is indicated to reduce deep wrinkles as much as 98% retaining the natural firmness of the skin.    Purchasing >>

Who is a good candidate for this product?

  • All men and women showing signs of aging and experiencing dark circles, fine lines, wrinkles, and puffiness around the eyes.
  • Ideal for people facing problems of dry skin.

How effective is the Eye Complex?

The clinical studies shown below prove the drastic influence of C12-15 Alkyl Benzoate, Tribehenin, Ceramide 2, PEG 10 Rapseed Sterel, Palmiteyl Oligopeptide, Hydrolyzed Rice Bran Protein, Glycine Soja Protein, Oxido Reductases andCeramide3 in reducing circles and deep wrinkles as much as 98% retaining the natural firmness of the skin.

Cosmetic Benefits of Vitamin K:

Clinical uses of vitamin K in the past have been directly linked with its ability to influence coagulation. Studies also showed that topical application of vitamin K decreased healing time for bruises, speeding the process by 4 or 5 days.

Use of an effective Vitamin K formulation can help fade or reverse mild vascular lesions. Telangeictasia of the face will respond within 2-3 months, whereas spider veins on the legs may take up to 6 months to respond. Vitamin K can also be used on Rosacea to help decrease redness and broken capillaries. It is also very effective at fading under-eye circles caused by dark blood vessels underlying the skin.

Cosmetic Benefits of C12-15 Alkyl Benzoate, Tribehenin, Ceramide 2, PEG 10 Rapseed Sterel, Palmiteyl Oligopeptide:
  • A new anhydrous ingredient based on peptide technology, utilizes a Matrikine-Ceramide 2 concept to combat aging and smooth out wrinkles.
  • It helps attract cells to sites that need repair and contributes to the reconstruction of the dermis.
  • Ceramide 2 strengthens and repairs the skin’s barrier. It improves cell cohesion, enhancing water retention and reducing skin dryness.
  • Ceramide 2 is involved in moisturization maintenance and the cohesion and renewal of the epidermis.
  • Has significant corrective and reparative effect on wrinkles and crow’s feet.

Clinical Study:

Pigmented products tend to accentuate the appearance of wrinkles and skin dryness rather than mask them. That’s why we used a foundation to evaluate the anti-wrinkling efficacy of this peptide. After only applying it once a day, for 56 days the results were dramatic:

  • Volume of main wrinkle reduced on average by 13.7% and reached as much as 36%.
  • Depth of main wrinkle reduced on average by 10.1% and as much as 27%.
  • Surface occupied by deep wrinkles reduced on average by 40.3% and as much as 98%.
  • Surface occupied by medium wrinkles reduced on average by 24.5% and as much as 86%.

Self Assessment:

  • 75% of the volunteers stated that the product smoothes the skin.
  • 52% observed a decrease in wrinkles and crows feet.

Cosmetic Benefits of Hydrolyzed Rice Bran Protein, Glycine Soja Protein, Oxido Reductases:
  • An active ingredient that reduces dark circles and puffiness around the eyes.
  • It improves micro-circulation, strengthens native collagen and elastin matrix, and reduces the presence of free radicals to delay the visible signs of premature aging.
  • Exerts a positive localized effect on the hemodynamic properties of the blood to improve oxygen supply to the tissue.
  • The complex inhibits elastase and collagenases, thereby reducing the effects of chronic UV radiation on the connective tissue, to help the skin retain its natural texture.

    Hydrolyzed Rice Bran Protein, Glycine Soja Protein, Oxido Reductases:


    A 35% reduction of dark circles around the eye was observed after 8 weeks of treatment by Hydrolyzed Rice Bran Protein, Glycine Soja (Soybean) Protein, Oxido Reductases.


    A reduction of eye puffiness of approximately 32% was observed after 8 weeks of treatment with 5% Hydrolyzed Rice Bran Protein, Glycine Soja (Soybean) Protein, Oxido Reductases.


    *All studies were conducted on Hydrolyzed Rice Bran Protein, Glycine Soja Protein, Glycine Soja Protein, Oxido Reductases and are not generated on Eye Complex products as a whole. In a clinical study, Hydrolyzed Rice Bran Protein, Glycine Soja Protein, Glycine Soja Protein, Oxido Reductases reduced deep wrinkles by as much as 68% over a period of six months. Results may vary.

Cosmetic Benefits of Ceramide 3:
  • Reinforces the natural lipid barrier of the skin.
  • Improves long-term moisturization and protects the skin from external influences.
  • Repairs and protects damaged hair (mechanical properties, liveliness, combability, shine).
  • Human skin identical molecule.
  • Natural product with high purity.
  • Active at low concentrations.

Ceramide 3 [Efficacy Studies]

Hydration of the skin

Two Ceramide 3 formulations (0.05% and 0.5%), and a control product were applied on the forearms of volunteers twice/day for 7 consecutive days. During the application week Ceramide 3 resulted in a statistically significant increase in water retention capacity of the skin compared to the Control. A dose-response effect with 0.05% and 0.5% Ceramide3 was seen. After the application was ceased, areas treated with the Control showed a rapid decrease in hydration.



Transepidermal water loss

In a second study, two Ceramide 3 formulations (0.2% and 0.5%), and a control product were applied on the forearms of volunteers twice/day for 7 consecutive days. The graph shows the TEWL (%) compared to pretreatment. After 7 days of application on healthy skin, no disturbance of the normal skin physiology was seen. Application of Ceramide 3 does not occlude the skin. After irritation with SDS, untreated skin and areas treated with the Control showed a lower increase in TEWL after SDS, demonstrating the protective effect of Ceramide3 on the skin.



All studies were conducted on Ceramide 3 and are not generated on Eye Complex products as a whole. In a clinical study, Ceramide3 reduced deep wrinkles by as much as 68% over a period of six months. Results may vary.

Sunflower oil: A light oil rich in vitamins and minerals.

Olive oil: An excellent addition to a blend for mature or dry skin.

Vitamin E Acetate: Vitamin E is widely recognized for its antioxidant activities. It has demonstrated immune-enhancing effects. It may also help protect skin from ultraviolet irradiation.

Dimethyethanolamine (DMAE): Shows remarkable effects when applied topically to skin, resulting in the reduction of fine lines and wrinkles.

Calcarea Carbonica, Graphites: Carbonica is useful for acne, eczema, hormonal imbalances, cracked skin on the hands and poor circulation. Graphites are beneficial for skin ailments, such as dry painful cracked skin, acne, skin sores, eczema, keloid, fibroma, wens, skin tags, slow healing wounds and scar tissue.

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